Eric Dane cause of death: Grey's Anatomy's ‘McSteamy’ passes away at 53 — what is ALS aka Lou Gehrig’s Disease?

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Lou Gehrig’s Disease or ALS is a progressive disease that attacks nerve cells controlling muscles throughout the body.

FILE - Eric Dane poses backstage at the TNT and TBS Network 2014 Upfront Presentations at Madison Square Garden, May 14, 2014, in New York. (Photo by Evan Agostini/Invision/AP, File)(Evan Agostini/Invision/AP)

Eric Dane cause of death: Eric Dane, the celebrated actor best known for his role as McSteamy in “Grey’s Anatomy”, passed away on Thursday, February 19. He was 53.

The actor died from amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, less than a year after he announced his diagnosis in April 2025.

Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight, his representatives said.

"He spent his final days surrounded by dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his world,” said a statement that requested privacy for his family.

What is ALS aka Lou Gehrig’s Disease?

Lou Gehrig’s Disease or ALS is a progressive disease that attacks nerve cells controlling muscles throughout the body.

ALS gradually destroys the nerve cells and connections needed to walk, talk, speak and breathe. Most patients die within three to five years of a diagnosis.

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